3-oxoacyl-[acyl-carrier-protein] synthase activity [GO_0004315]

Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].
Tags:

3-oxoacyl-[acyl-carrier-protein] synthase activity

ID: GO_0004315

Class

Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].

Note that this activity is responsible for the chain-elongation step of dissociated (type II) fatty-acid biosynthesis, i.e. the addition of two C atoms to the fatty-acid chain. Can use fatty acyl thioesters of ACP (C2 to C16) as substrates, as well as fatty acyl thioesters of Co-A (C4 to C16).

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Classification

Alternative Names

Synonym Scope Reference
acyl-malonyl acyl carrier protein-condensing enzyme activity related synonym 2.3.1.41
beta-ketoacyl acyl carrier protein synthase activity related synonym 2.3.1.41
3-oxoacyl-acyl-carrier-protein synthase activity related synonym 2.3.1.41
acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity related synonym 2.3.1.41
acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating) related synonym 2.3.1.41
beta-ketoacyl-ACP synthetase activity related synonym 2.3.1.41
beta-ketoacyl-[acyl carrier protein] synthase activity related synonym 2.3.1.41
beta-ketoacyl-acyl carrier protein synthetase activity related synonym 2.3.1.41
beta-ketoacyl synthetase activity related synonym 2.3.1.41
beta-ketoacylsynthase activity related synonym 2.3.1.41
3-ketoacyl-acyl carrier protein synthase activity related synonym 2.3.1.41
beta-ketoacyl-acyl carrier protein synthase activity related synonym 2.3.1.41
beta-ketoacyl-acyl-carrier-protein synthase II activity narrow synonym
3-oxoacyl-acyl carrier protein synthase I activity narrow synonym 2.3.1.179
beta-ketoacyl-ACP synthase II activity narrow synonym 2.3.1.179
beta-ketoacyl-acyl-carrier-protein synthase I narrow synonym 2.3.1.41
beta-ketoacyl-ACP synthase I activity narrow synonym 2.3.1.41
condensing enzyme activity broad synonym 2.3.1.41
fatty acid condensing enzyme activity broad synonym 2.3.1.41
ketoacyl-ACP synthase activity exact synonym
3-oxoacyl-[acyl-carrier protein] synthase activity exact synonym
3-oxoacyl-ACP synthase activity exact synonym

References