aminoacyl-tRNA ligase activity [GO_0004812]

Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.

aminoacyl-tRNA ligase activity

ID: GO_0004812

Class

Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.

Note that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA.

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Classification

Alternative Names

Synonym Scope Reference
ligase activity, forming aminoacyl-tRNA and related compounds broad synonym
aminoacyl-tRNA synthetase activity exact synonym hjd
aminoacyl-tRNA synthetase auxiliary protein activity related synonym

References