class I DNA-(apurinic or apyrimidinic site) endonuclease activity [GO_0140078]
Catalysis of the cleavage of an AP site 3’ of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3’-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5’-phosphate.
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ID: GO_0140078
Class
Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| AP endonuclease class I activity | related synonym | |
| AP lyase activity | related synonym | |
| DNA-(apurinic or apyrimidinic site) 5’-phosphomonoester-lyase activity | exact synonym | |
| class I DNA-(apurinic or apyrimidinic site) lyase activity | exact synonym | |
| DNA-(apurinic or apyrimidinic site) lyase activity | exact synonym | |
| AP site-DNA 5’-phosphomonoester-lyase activity | exact synonym | |
| class I AP endonuclease activity | related synonym |
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