DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity [GO_0072587]
Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity
ID: GO_0072587
Class
Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
Open in VFB 3D Browser →Classification
- ATPase activator activity
- DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity
- enzyme activator activity
Relationships
- positively regulates: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
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