histone H4K20 methyltransferase activity [GO_0042799]
Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group to the lysine residue at position 20 of the histone H4 protein.
histone H4K20 methyltransferase activity
ID: GO_0042799
Class
Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group to the lysine residue at position 20 of the histone H4 protein.
Note that the residue position corresponds to the canonical human H4 histone (UniProtKB:P02309); this residue is conserved across all eukaryotes. Note that the initiation methionine is cleaved, so the first residue is S1.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| histone H4K20 methylase activity | broad synonym | |
| histone lysine N-methyltransferase activity (H4-K20 specific) | exact synonym | |
| histone methylase activity (H4-K20 specific) | exact synonym | |
| histone H4K20 methylation | exact synonym | |
| histone methyltransferase activity (H4-K20 specific) | exact synonym | |
| histone-H4K20 methyltransferase activity | exact synonym | |
| histone H4 lysine 20-specific methyltransferase activity | exact synonym |
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